Help us fund a cure for GABRB2

Cure GABRB2 has raised $89,426 out of their goal of $100,000

$89,426 / $100,000
89% of goal
56 supporters
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What is GABRB2? 


GABRB2 is a rare neurological condition that causes seizures, movement disorders, and a range of disabilities including severe global disabilities.  Seizures are often resistant to medication and can begin at infancy.  In some children, the numbers of seizures in a day can exceed 100.  Many other challenges for these children and young adults include frequent hospitalizations, feeding tubes, sleep disorders, behavior issues, lack of head or body control, and visual impairments.  Many are unable to walk and are non-verbal.



How it Works


The GABRB2 gene encodes the beta-2 subunit of a GABA-A receptor.  GABA is the primary inhibitory neurotransmitter in the brain and acts at GABA receptors, counteracting the overexcitement of neurons.  This gene mutation can cause the loss of function of the GABA-A receptor containing the beta-2 subunit.  The beta-2 subunit is contained in more than half of all GABA-A receptors in the brain.  


The Search for a Cure


Parents who receive this diagnosis for their children are told that there are no treatments available due to the rarity of the condition, and often find our online parent support group searching for answers on their own.  There is little incentive for companies to develop drugs for ultra-rare conditions like GABRB2.  We are raising money to fund research with the goal of finding a cure for this condition.



You can help fund a cure for our kids today.


With your generous support, we can fund research and hopefully find a cure for all children diagnosed with GABRB2. Help our kids today!


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